For more than 50 years, Los Robles Health System has led the way in providing a full range of diagnostic and treatment options for all areas of cardiovascular and neurovascular care, leading to the best outcomes for our patients. Our outcomes for heart and neurovascular care are consistently in the nation’s top 10 percent and we participate in multiple cutting-edge clinical trials.

Our multi-disciplinary cardiovascular team focuses on heart and vascular health, from diagnosis of heart disease to management of heart failure and everything in between.

Our dedicated multidisciplinary team of neurovascular professionals utilize state-of-the-art technology and clinical practices in neuroimaging, endovascular device development and advanced techniques in image guided minimally invasive surgery.

Our first and most important responsibility is to our patients and their families, ensuring they receive the best healthcare possible.

Heart clinical trials

Los Robles Health System conducts research for a wide range of cardiovascular disorders and offers patients opportunities to participate in research and clinical trials. Below is more information about clinical trials currently underway at Los Robles.

4C Medical Technologies Alta Valve Early Feasibility

To assess safety and performance of the Alta Valve for the treatment of severe MR in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery. (NCT03997305)

Learn more about Alta Valve

Abbott Portico NG

Evaluation of the Portico™ NG Transcatheter Aortic Valve in High and Extreme Risk Patients with Symptomatic Severe Aortic Stenosis. (NCT 02701283)

Learn more about Abbott Portico NG

Abbott Repair MR

Percutaneous MitraClip™ Device or Surgical Mitral Valve Repair in Patients with Primary Mitral Regurgitation who are Candidates for Surgery (REPAIR-MR). (NCT 04198870)

Learn more about the Abbott Repair MR Trial

Abbott SUMMIT

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve Replacement System for the Treatment of Symptomatic Mitral Regurgitation. (NCT 03133274)

Learn more about the Abbott SUMMIT Trial

Abbott TRILUMINATE Pivotal

Clinical TRIal to EvaLUate Cardiovascular OutcoMes IN PAtients Treated with the Tricuspid ValvE Repair System Pivotal. Evaluate the safety and effectiveness of the TriClip™ device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR) who have been determined by the site’s local heart team to be at intermediate or greater estimated risk for mortality with tricuspid valve surgery. (NCT 03904147)

Learn more about the Abbott TRILUMINATE Pivotal Trial

atHeart Medical ASCENT ASD

Evaluation of the safety and efficacy of the atHeart Bioresorbable Septal Occluder (CBSO) to treat patients with clinically significant secundum atrial septal defect. Patients with clinically significant secundum atrial septal defect, defined as presence of right ventricular overload who, in the judgment of the treating physician, require, and are suitable for, transcatheter device closure (ASCENT-ASD STUDY) (NCT 04591392)

Learn more about the atHeart Medical Clinical Trial

Bioventrix ALIVE trial

American Less Invasive Ventricular Enhancement -The Revivent system for the treatment of post infarction (AMI) ischemic heart failure through catheter based ventricular repair. (NCT 02931240)

Learn more about the Bioventrix ALIVE Trial

Boston Scientific Champion AF

WATCHMAN FLX versus NOAC for Embolic Protection in the Management of Patients with Non-Valvular Atrial Fibrillation. (NCT 04394546)

Learn more about Champion AF Trial

CLASP IID + IIF

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective, multicenter, randomized, controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip™ in patients with mitral regurgitation. (NCT 03706833)

Learn more about the CLASP IID + IIF Trial

EMBLOK Protection System

Innovative Cardiovascular Solution Emblok IDE: Embolic Protection system during TAVR: A Prospective, Randomized, Multicenter Evaluation of the Safety and Effectiveness of the EMBLOK Embolic Protection System during Transcatheter Aortic Valve Replacement. (NCT 05295628)

Learn more about EMBLOK

HighLife Medical HIGHLIFE HL-2019-01

An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System. (NCT 04029337)

Learn more about the Highlife Medical HL-2019-01 Trial

Medtronic SMART

SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial. The purpose of this trial is to generate clinical evidence on valve safety and performance of self‐expanding (SE) versus balloon‐expandable (BE) transcatheter aortic valve replacement (TAVR) in subjects with a small aortic annulus and symptomatic severe native aortic stenosis. (NCT 04722250)

Learn more about SMART

Neovasc Medical Inc. CORSIRA-II

To demonstrate the safety and effectiveness of the Reducer system for treatment of patients with refractory angina pectoris treated with maximally tolerated guideline-directed medical therapy wo demonstrate objective evidence of reversible. myocardial ischemic in the distribution of the left coronary artery and who are deemed unsuitable for revascularization. (NCT05102019)

Learn more about CORSIRA II

Occlutech USA OccluFlex PFO

Prospective Randomized Multicenter controlled clinical investigation comparing PFO Outcomes of the Occlutech Flex II PPFU Occluder to Standard of Care PFO Occlusion (NCT05069558

Learn more about OccuFlex PFO

V-WAVE RELIEVE-HF TRIAL

Provide reasonable assurance of safety and effectiveness of the V-Wave Interatrial Shunt System to reduce lung congestion symptoms and improve clinical outcomes in a certain high-risk subset of symptomatic patients suffering from heart failure. (NCT 03499236)

Learn more about the RELIEVE-HF TRIAL

Contact us

Contact us to learn more about these and upcoming clinical trials at Los Robles Health System.

Mane Arabyan
Cardiovascular Research Coordinator
HCA Research Institute at Los Robles Health System
227 West Janss Rd., Suite 340
Phone: (805) 796-3746
Email: Email Mane

Maria Cabral-Aoki – Cardiovascular Research Coordinator
HCA Research Institute at Los Robles Health System
227 West Janss Rd., Suite 340
Thousand Oaks, CA 91360
Phone: (805) 208-3413
Email: Email Maria

Neurovascular clinical trials

In close collaboration with HCA Research Institute, Los Robles Health System is engaged in several cutting-edge trials, with many more in the pipeline:

The APPLY Study

Sponsor: Vascular Neurology of Southern California, Inc.

APPLY STUDY is an investigator-initiated prospective, real-world, single-center, post-market study conducted in Thousand Oaks, California. The purpose of this study is to demonstrate the efficacy and safety of the Balt OptimaTM Coil System in the treatment of intracranial aneurysms. (NCT 04499508)

Learn more about the APPLY Study

CLEAR Study

Sponsor: VesalioStryker

A prospective, open label, single-arm 90-day study designed to assess the safety, performance, and efficacy of thrombus removal in subjects presenting with acute ischemic stroke with the NeVa stent retrievers. (NCT 04514562)

Learn more about the CLEAR Study

EvaQ Study

Sponsor: MiVi Neuroscience

EvaQ is a prospective, multi-center, single arm study meant to assess the safety and efficacy of the Q Revascularization System to remove thrombi and emboli from the neurovasculature in patients experiencing an acute ischemic stroke. (NCT 04437682)

Learn more about the EvaQ Study

STEM Trial

Sponsor: Balt USA, LLC

The STEM Trial is a prospective, international, multi-center, randomized study established in effort to provide assessment of the safety and effectiveness of Middle Meningeal Artery (MMA) embolization of Chronic Subdural Hematoma. (NCT 04410146)

Learn more about the STEM Trial

SUCCESS Study

Sponsor: Rapid Medical

SUCCESS is a multi-center, single arm, prospective, post-market surveillance study aimed to assess safety and performance of the Comaneci Embolization Assist Device as it is indicated for use as a temporary endovascular device used to assist in the coil embolization of wide-necked intracranial aneurysms. (NCT 04518670)

Learn more about the SUCCESS Study

SURF Study

Sponsor: Penumbra, Inc.

The SURF Study is a prospective, multi-center, real-world, post-market study with sites across North America that aims to establish the safety and efficacy of the Penumbra SMART COIL System, this includes the WAVE Extra Soft Coils in the treatment of intracranial aneurysms. The system works as a fill and finish coil that is meant to adequately embolize various neurovascular lesions. (NCT 04106583)

Learn more about the SURF Study

TESLA Trial

Sponsor: Investigator-Initiated Study funded by Genentech, Cerenovus, Medtronic, Penumbra, Stryker

The TESLA Trial is a prospective, randomized, open-label, blinded endpoint study that aims to determine the efficacy of intra-arterial mechanical thrombectomy in the treatment of acute ischemic stroke due to a large vessel occlusion in the anterior circulation that are currently not candidates for thrombectomy. (NCT 03805308)

Learn more about the TESLA Trial

Contact us

Contact us to learn more about these and upcoming clinical trials at Los Robles Health System.

Claire Hozinsky
Clinical Nurse Manager, Interventional Radiology
HCA Research Institute at Los Robles Health System
Phone:
(805) 796-1836
Email